
Thermo Fisher Scientific CD28 Monoclonal Antibody (CC220)
소 및 T세포 연구용 CD28 단클론 항체(CC220). Flow Cytometry 및 Functional Assay에 사용 가능. 단클론 Mouse IgG1 형식으로 제작되어 높은 특이성과 재현성을 제공. Protein A로 정제된 1 mg/mL 액상 형태, -20°C 보관.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CC220 |
| Immunogen | Plasmid DNA encoding the bovine CD28 gene |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745304 |
Product Specific Information
Mouse anti-Bovine CD28, clone CC220 recognizes the bovine homologue of human CD28, a co-stimulatory cell surface molecule expressed by T cell subsets.
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T cell-specific surface glycoprotein. It belongs to the immunoglobulin superfamily and is constitutively expressed on most peripheral blood T lymphocytes. CD28 acts as a critical co-stimulatory receptor that provides the second activation signal to T cells by binding CD80 and CD86 on antigen-presenting cells. It prevents T cells from entering an anergic or apoptotic state. In murine lymphoid organs and blood, all CD4+ and CD8+ T cells express CD28, with varying expression levels depending on maturation stage. CD28 dysfunction is associated with diseases such as mycosis fungoides and Sezary’s Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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