Thermo Fisher Scientific GPD2 Monoclonal Antibody (2C11-1F4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2C11-1F4

Immunogen

GPD2 (AAH19874, 1 a.a. approximately 378 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPD2,uniProtId:P43304-1,ncbiNodeId:9606,antigenRange:1-727,antigenLength:727,antigenImageFileName:H00002820-M02_GPD2_P43304-1_House_mouse.svg,antigenImageFileNamePDP:H00002820-M02_GPD2_P43304-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MAFQKAVKGT LVGGGALATV LGLSQFAHYR RKQMNLAYVK AADCISEPVN REPPSREAQL LTLQNTSEFD ILVIGGGATG SGCALDAVTR GLKTALVERD DFSSGTSSRS TKLIHGGVRY LQKAIMKLDI EQYRMVKEAL HERANLLEIA PHLSAPLPIM LPVYKWWQLP YYWVGIKLYD LVAGSNCLKS SYVLSKSRAL EHFPMLQKDK LVGAIVYYDG QHNDARMNLA IALTAARYGA ATANYMEVVS LLKKTDPQTG KVHVSGARCK DVLTGQEFDV RAKCVINATG PFTDSVRKMD DKDAAAICQP SAGVHIVMPG YYSPESMGLL DPATSDGRVI FFLPWQKMTI AGTTDTPTDV THHPIPSEED INFILNEV

Target Information

Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.