Thermo Fisher Scientific GPD2 Monoclonal Antibody (2C11-1F4)
Thermo Fisher Scientific의 GPD2 단클론 항체(2C11-1F4)는 인간 GPD2 단백질을 특이적으로 인식하는 Mouse IgG1 항체입니다. Western blot과 ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제되어 연구용으로 최적화되었습니다. -20°C에서 안정적으로 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C11-1F4 |
| Immunogen | GPD2 (AAH19874, 1 a.a. ~ 378 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAFQKAVKGT LVGGGALATV LGLSQFAHYR RKQMNLAYVK AADCISEPVN REPPSREAQL LTLQNTSEFD ILVIGGGATG SGCALDAVTR GLKTALVERD DFSSGTSSRS TKLIHGGVRY LQKAIMKLDI EQYRMVKEAL HERANLLEIA PHLSAPLPIM LPVYKWWQLP YYWVGIKLYD LVAGSNCLKS SYVLSKSRAL EHFPMLQKDK LVGAIVYYDG QHNDARMNLA IALTAARYGA ATANYMEVVS LLKKTDPQTG KVHVSGARCK DVLTGQEFDV RAKCVINATG PFTDSVRKMD DKDAAAICQP SAGVHIVMPG YYSPESMGLL DPATSDGRVI FFLPWQKMTI AGTTDTPTDV THHPIPSEED INFILNEV
Target Information
Mitochondrial glycerophosphate dehydrogenase (EC 1.1.99.5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD.
Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which transfers reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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