Thermo Fisher Scientific Phospho-Bid (Ser78) Polyclonal Antibody
Phospho-Bid (Ser78) 폴리클로날 항체로서 마우스 및 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Protein A로 정제된 고순도 액상 항체이며, 안정적인 PBS/glycerol 버퍼에 보존됩니다.
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Thermo Fisher Scientific Phospho-Bid (Ser78) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from mouse Bid around the phosphorylation site of Ser78 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. It is a member of the BCL-2 family of cell death regulators and mediates mitochondrial damage induced by caspase-8 (CASP8). CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria, triggering cytochrome c release. BID serves as a direct molecular link between caspase-8 activation and mitochondrial death machinery, acting as a pro-apoptotic member of the Bcl-2 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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