Thermo Fisher Scientific STING1/TMEM173 Recombinant Rabbit Monoclonal Antibody (STING1/8187R)
STING1/TMEM173 단백질을 인식하는 재조합 토끼 단클론 항체로, 인체 시료에 반응합니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, Protein A/G로 정제된 액상 형태입니다. NF-κB 및 IRF3 경로 연구 등 선천면역 신호 연구에 활용됩니다.
- 카탈로그번호
- 8187R-P1ABX
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | STING1/8187R |
| Immunogen | Recombinant fragment (around aa190–290) of human TMEM173 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
STING is a 379 amino acid signaling protein that plays a crucial role in innate immune signaling. It activates NF-κB and IRF3 pathways to induce type I interferon (IFN-α and IFN-β) expression, establishing an antiviral state. STING may also function as a translocon influencing interferon induction and mediates apoptotic signaling via association with MHC-II. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across most tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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