Thermo Fisher Scientific POM121 Polyclonal Antibody
Thermo Fisher Scientific의 POM121 Polyclonal Antibody는 인간 및 생쥐에 반응하며 Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 핵공복합체(NPC) 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific POM121 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human POM121 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.16 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792308 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (82%), Rat (81%).
- Positive Control: A549.
- Centrifuge briefly prior to opening the vial.
- Store product as a concentrated solution.
Target Information
POM121 (POM121 membrane glycoprotein), also known as POM121A or NUP121, is a 1,249 amino acid single-pass membrane protein belonging to the POM121 family.
Encoded by a gene on human chromosome 7q11.23, POM121 localizes to the nuclear and endoplasmic reticulum membranes.
It is an essential component of the nuclear pore complex (NPC), required for nuclear envelope formation and NPC biogenesis.
POM121 associates with the central spoke ring complex and anchors pore complex components to the membrane via its F-X-F-G repeat-containing domain.
Overexpression of POM121 induces formation of cytoplasmic annulate lamellae (AL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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