Thermo Fisher Scientific ELL Monoclonal Antibody (OTI3A8), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ELL is an elongation factor component of the super elongation complex (SEC), which enhances the catalytic rate of RNA polymerase II transcription by suppressing transient pausing at multiple DNA sites.
It is also part of the little elongation complex (LEC), regulating small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
ELL plays a critical role in stabilizing RNA polymerase II recruitment and early elongation prior to SEC assembly.
[UniProt: P55199-1]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.