Thermo Fisher Scientific PSME1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Positive test controls: MCF7, 22Rv1, BT-474, Mouse spleen, Mouse liver, Mouse lung, Mouse heart, Mouse thymus
• Immunogen sequence:
  MAMLRVQPEA QAKVDVFRED LCTKTENLLG SYFPKKISEL DAFLKEPALN EANLSNLKAP LDIPVPDPVK EKEKEERKKQ QEKEDKDEKK KGEDEDKGPP CGPVNCNEKI VVLLQRLKPE IKDVIEQLNL VTTWLQLQIP RIEDGNNFGV AVQEKVFELM TSLHTKLEGF HTQISKYFSE RGDAVTKAAK QPHVGDYRQL VHELDEAEYR DIRLMVMEIR NAYAVLYDII LKNFEKLKKP RGETKGMIY

Target Information

Proteolytic degradation is critical to maintaining appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, modulation of cell surface receptors, ion channels, cell cycle regulation, transcription, and signaling factors.
The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cytosol and nucleus. The 26S proteasome is an ATP-dependent, multisubunit complex (~2.5 MDa) composed of a 20S proteolytic core and 19S regulatory subunits.
Defects in this pathway are associated with diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.