Thermo Fisher Scientific C4B Monoclonal Antibody (OTI1B2), TrueMAB
인간 C4B 단백질을 인식하는 단일클론 항체로 Western blot에 최적화됨. Mouse IgG2a 형식의 TrueMAB이며, 액상 형태로 공급. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/BSA/glycerol 버퍼 구성. 연구용으로만 사용 가능.
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- pk
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Thermo Fisher Scientific C4B Monoclonal Antibody (OTI1B2), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B2 |
| Immunogen | Human recombinant protein fragment (aa 1100–1350 of human C4B, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The C4B gene encodes complement factor 4, a key component of the classical activation pathway.
This protein is produced as a precursor and cleaved into a trimer (alpha, beta, gamma chains) prior to secretion.
It mediates interactions between antigen-antibody complexes and complement components.
Cleavage of the alpha chain releases C4 anaphylatoxin, an inflammation mediator.
Deficiency of C4B is linked to systemic lupus erythematosus.
The gene is located in the MHC class III region on chromosome 6 and may exist in multiple haplotypes (1–3 copies).
Variants include long and short forms due to the presence or absence of a 6.4 kb HERV-K retrovirus in intron 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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