Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI8C8), TrueMAB
인간 PD-L1을 인식하는 단클론 항체로, Flow Cytometry에 적합합니다. TrueMAB 형식의 고순도 항체이며 Affinity chromatography로 정제되었습니다. PBS 용액 형태로 제공되며 보존제가 포함되어 있지 않습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA813015
- 판매단위
- pk
카탈로그
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8C8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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