Thermo Fisher Scientific CD34 Monoclonal Antibody (1H6), Biotin
Thermo Fisher CD34 단클론 항체(1H6), Biotin은 개(Canine) CD34 단백질을 인식하는 Mouse IgG1 형 항체로, Biotin 결합형입니다. 유세포분석(Flow Cytometry)에 적합하며, 혈액줄기세포 및 내피세포 표지 연구에 활용됩니다. 단백질 A 정제, PBS/BSA 저장용액, 4°C 또는 -20°C 보관.
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Thermo Fisher Scientific CD34 Monoclonal Antibody (1H6), Biotin
Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat - 1/5
Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6 |
| Immunogen | Canine CD34 fusion protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745317 |
Additional Formats
Product Specific Information
Mouse anti-dog CD34 antibody, clone 1H6 recognizes the canine homologue of CD34, a glycosylated type I transmembrane protein (~110 kDa) expressed on endothelial cells and hematopoietic stem cells (McSweeney et al., 1998).
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) found in many stem cell populations. It serves as a stem cell marker with reversible expression on human hematopoietic stem cells. CD34 may function as a receptor regulating adhesion, differentiation, and proliferation of stem and progenitor cells. It possibly mediates stem cell attachment to the bone marrow matrix or stromal cells and may act as a scaffold for glycans binding to lectins. The intracellular domain is phosphorylated by protein kinase C, suggesting a role in signal transduction.
Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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