Thermo Fisher Scientific Desmocollin 3 Polyclonal Antibody
Human Desmocollin 3 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로 Western blot에 적합. N-말단 합성 펩타이드로 면역화되어 높은 특이성과 반응성을 제공. 액상 형태로 공급되며 -20°C에서 장기 보관 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human DSC3 (aa 144–193) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884321 |
Product Specific Information
- Immunogen sequence: MQENSLGPFP LFLQQVESDA AQNYTVFYSI SGRGVDKEPL NLFYIERDTG
- For short-term use: store at 2–8°C up to 1 week.
- For long-term storage: store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Predicted homology:
- Cow: 100%
- Dog: 93%
- Horse: 93%
- Human: 100%
- Mouse: 86%
- Pig: 93%
- Rabbit: 93%
- Rat: 93%
Target Information
Desmosomes are cell–cell junctions found in epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These gene family members are located in a cluster on chromosome 18. Desmocollin 3 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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