Thermo Fisher Scientific Desmocollin 3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: MQENSLGPFP LFLQQVESDA AQNYTVFYSI SGRGVDKEPL NLFYIERDTG
• For short-term use: store at 2–8°C up to 1 week.
• For long-term storage: store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology:
  • Cow: 100%
  • Dog: 93%
  • Horse: 93%
  • Human: 100%
  • Mouse: 86%
  • Pig: 93%
  • Rabbit: 93%
  • Rat: 93%

Target Information

Desmosomes are cell–cell junctions found in epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These gene family members are located in a cluster on chromosome 18. Desmocollin 3 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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