Thermo Fisher Scientific MAP2K1 Monoclonal Antibody (OTI3H3), TrueMAB
MAP2K1(MEK1) 단백질을 표적하는 Mouse monoclonal antibody로, WB, IHC(P), ICC/IF에 적합합니다. Human, Mouse, Rat, Dog에 반응하며, Affinity chromatography로 정제된 1 mg/mL 액상 제품입니다. 세포 성장 및 분화 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H3 |
| Immunogen | Full length human recombinant protein of human MAP2K1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by various growth factors, cytokines, membrane depolarization, and calcium influx. Activation occurs via phosphorylation at serine 218 and 222 residues by Raf1. It plays roles in stress response signaling, apoptosis, and cytokine-induced proliferation. Mutations in MAP2K1 can cause cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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