Thermo Fisher Scientific HRG Recombinant Rabbit Monoclonal Antibody (28)

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the rabbit immune repertoire

This antibody shows specificity for Human HPRG/HRG.

Target Information

HRG contains two cystatin-like domains and is found in plasma and platelets. Although its precise physiological function is not fully determined, it is known to bind heme, dyes, and divalent metal ions. HRG interacts with heparin, thrombospondin, and plasminogen, and can inhibit fibrinolysis and modulate coagulation, suggesting a potential prothrombotic role. Mutations in the HRG gene can lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.