Thermo Fisher Scientific ATP Citrate Lyase Monoclonal Antibody
인간 ACLY 재조합 단백질을 면역원으로 한 Thermo Fisher Scientific의 ATP Citrate Lyase 단클론 항체. Western blot에 적합하며 다양한 세포주에서 양성 반응. 액상 형태로 -20°C 보관, 연구용으로만 사용.
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Thermo Fisher Scientific ATP Citrate Lyase Monoclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human ACLY |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Product Specific Information
Positive Samples: HeLa, K-562, COS-7, HepG2, Raji, NIH/3T3, Mouse kidney
Target Information
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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