Thermo Fisher Scientific Mirikizumab Humanized Recombinant Human Monoclonal Antibody
Mirikizumab은 인간화된 IgG4 단일클론 항체로 IL-23의 p19 서브유닛을 표적합니다. 면역 관련 질환 연구에 사용되며, ELISA에 적합합니다. CHO 세포에서 발현된 재조합 항체로, Protein A로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG4, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human IL23A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.76 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911315 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Mirikizumab is a humanized IgG4 monoclonal antibody that targets the p19 subunit of IL-23. It is under development for various immune diseases, including psoriasis, ulcerative colitis (UC), and Crohn’s disease (CD). Among these, treatment of moderate to severe plaque psoriasis is in phase III clinical trials.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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