Thermo Fisher Scientific Cofetuzumab Humanized Recombinant Human Monoclonal Antibody
인간화된 재조합 단일클론 항체로, PTK7 단백질을 표적화하여 연구용으로 사용됩니다. ELISA 등 다양한 응용에 적합하며, CHO 세포에서 발현된 IgG1, kappa 형식의 항체입니다. 단백질 A/G로 정제되었으며, 보존제가 포함되지 않은 PBS 용액 형태로 제공됩니다.
- 판매단위
- pk
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human PTK7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.11 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911316 |
Product Specific Information
- Endotoxin level < 0.01 EU/µg by LAL method
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for one week.
- Store at -20 to -80°C for twelve months from the date of receipt.
Target Information
Cofetuzumab is a biosimilar that targets PTK7. CCK4 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of the Tyr protein kinases, it likely lacks catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta, and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart, and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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