Thermo Fisher Scientific IVNS1ABP Polyclonal Antibody
Thermo Fisher Scientific의 IVNS1ABP 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot에 사용 가능하며, 액상 형태로 1 mg/mL 농도입니다. IVNS1ABP 단백질의 내인성 수준을 검출하며, 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5100582
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IVNS1ABP (Accession Q9Y6Y0), corresponding to amino acid residues T403–R453 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850090 |
Product Specific Information
Antibody detects endogenous levels of total IVNS1ABP.
Target Information
IVNS1ABP is a protein coding gene involved in many cellular functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization, and protein ubiquitination.
It stabilizes actin filaments by associating with F-actin through Kelch repeats, protecting cells from actin destabilization-induced cell death.
Functions as a modifier of the AHR pathway, increasing AHR concentration available for transcription activation.
Acts as a negative regulator of the BCR(KLHL20) E3 ubiquitin ligase complex, preventing proteolysis of tumor suppressors PML and DAPK1.
Inhibits pre-mRNA splicing in vitro.
During microbial infection, IVNS1ABP participates in alternative splicing of influenza A virus M1 mRNA via interaction with HNRNPK, facilitating generation of viral M2 protein.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-100582_IVNS1ABP_Q9Y6Y0-1_Rabbit.svg, PA5-100582_IVNS1ABP_Q9Y6Y0-1_Rabbit_PDP.jpeg)
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