ELK Biotechnology NCK1 rabbit pAb
NCK1 rabbit pAb는 인간 및 마우스 단백질에 반응하는 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 세포 내 신호전달 관련 단백질을 검출하며, 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
NCK1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 41 kD |
| GeneID (Human) | 4690 |
| Human Swiss-Prot No | P16333 |
| Species Reactivity | Human; Mouse |
세포 내 위치
Cytoplasm, Endoplasmic reticulum, Nucleus.
Mostly cytoplasmic, but shuttles between the cytoplasm and the nucleus.
Import into the nucleus requires interaction with SOCS7.
Predominantly nuclear following genotoxic stresses such as UV irradiation, hydroxyurea, or mitomycin C treatments.
배경 정보
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains.
It acts as an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS.
Alternatively spliced transcript variants encoding different isoforms have been identified.
[Provided by RefSeq, Jun 2010]
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