ELK Biotechnology CNTFR rabbit pAb
CNTFR rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 다클론 항체로, WB 및 ELISA에 적합합니다. 세포막에 위치한 CNTFR 단백질을 인식하며, 신경세포 생존 및 분화 연구에 유용합니다. -20°C 보관 시 1년 안정적으로 유지됩니다.
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제품명
CNTFR rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| Gene ID (Human) | 1271 |
| Human Swiss-Prot No. | P26992 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Species Reactivity | Human; Mouse; Rat |
제품 설명
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation, and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
[provided by RefSeq, May 2011]
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