
ELK Biotechnology CABYR rabbit pAb
CABYR 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 인산화 시 칼슘 결합 활성을 가지며 정자 섬유초에 위치. 인간, 랫드, 마우스 반응성. -20°C에서 1년 보관 가능.
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CABYR rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CABYR rabbit pAb |
| Applications | WB; ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 54 kD |
| Gene ID (Human) | 26256 |
| Human Swiss-Prot No. | O75952 |
| Cellular Localization | Cytoplasm, cytoskeleton, cell projection, cilium, flagellum. Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella. Isoform 1: Nucleus, cytoplasm, cell projection, cilium, flagellum. Isoform 3: Nucleus, cytoplasm, cell projection, cilium, flagellum. Isoform 5: Nucleus, cytoplasm, cell projection, cilium, flagellum. According to PubMed:15752768, isoforms 1, 3, and 5 are both nuclear and cytoplasmic. |
| Species Reactivity | Human; Rat; Mouse |
Background
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. (Provided by RefSeq, Jul 2013)
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