ELK Biotechnology B4GT7 rabbit pAb
B4GT7 단백질을 인식하는 토끼 폴리클로날 항체로 WB 및 ELISA에 적합. 인간 및 생쥐 시료 반응성. 골지체 단백질 검출용으로 사용 가능. -20°C에서 1년 보관 가능. 고순도 IgG, 1 mg/ml 농도.
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제품명
B4GT7 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 35 kD |
| Gene ID (Human) | 11285 |
| Human Swiss-Prot No | Q9UBV7 |
| Species Reactivity | Human; Mouse |
| Cellular Localization | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cis cisternae of Golgi stack. |
Background
This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus, which remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1–beta4GalT6 and is located in cis-Golgi instead of trans-Golgi.
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