Thermo Fisher Scientific Phospho-GEF-H1 (Ser885) Polyclonal Antibody
인간 GEF-H1 단백질의 Ser885 인산화 부위에 특이적인 폴리클로날 항체로, Western blot에 적합합니다. Rabbit IgG로 제조되었으며 액상 형태, 1 mg/mL 농도입니다. 세포 신호전달 및 GTPase 활성 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Rho/Rac Guanine Nucleotide Exchange Factor 2 around the phosphorylation site of Ser885 (R-R-SP-L-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555508 |
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli acting through G protein-coupled receptors.
GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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