Thermo Fisher Scientific GEF-H1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GEF-H1 (Rho/Rac GEF2). Validated for Western blot (1:500–1:1,000). Supplied as liquid, unconjugated, 1 mg/mL. Stored at -20°C and shipped on wet ice. For research use only.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic non-phosphopeptide derived from human Rho/Rac Guanine Nucleotide Exchange Factor 2 around the phosphorylation site of Ser885 (R-R-SP-L-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555509 |
Target Information
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that act through G protein-coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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