Thermo Fisher Scientific KYNU Monoclonal Antibody (OTI1H1), TrueMAB
인간 KYNU 단백질(아미노산 1-216)에 특이적인 마우스 단클론 항체입니다. 파라핀 절편 IHC(P)에서 1:150 희석으로 검증되었습니다. 동결건조 형태로 제공되며, 재구성 시 약 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–216 of human KYNU produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Kynureninase is a pyridoxal-5′-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively.
It plays a key role in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.
Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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