Thermo Fisher Scientific CCDC134 Monoclonal Antibody (04)
인간 CCDC134 단백질을 인식하는 Mouse IgG1 단일클론 항체. ELISA에 적합하며 보존제가 없는 액상 형태. 단기 4°C, 장기 -20°C 보관 권장. 단백질 A로 정제된 고순도 항체로 연구용에 적합.
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Applications
ELISA
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 04 |
| Immunogen | Recombinant Human CCDC134 protein (Met1–Leu229) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785910 |
Product Specific Information
- This product is preservative free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human CCDC134.
Target Information
The coiled-coil domain is a common protein motif involved in protein oligomerization, found in transcription factors and intermediate filaments.
CCDC134 is a secretory protein known to inhibit the transcriptional activity of Elk1. Overexpression of CCDC134 inhibits phosphorylation of Erk and JNK/SAPK, but not p38 MAPK.
Conversely, siRNA against CCDC134 activates Elk1 transcriptional activity and phosphorylation of Erk and JNK/SAPK, suggesting an inhibitory role of CCDC134 in MAPK-mediated Elk1 transcription.
CCDC134 is widely expressed in normal adult tissues, tumors, and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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