Thermo Fisher Scientific IL17RA Recombinant Rabbit Monoclonal Antibody (R004)
인간 IL-17RA를 인식하는 재조합 토끼 단클론 항체로, Flow Cytometry 및 Neutralization 실험에 최적화됨. 고순도 Protein A 정제 제품이며, 보존제가 포함되지 않음. 연구용으로만 사용 가능하며, 염증성 및 자가면역 질환 연구에 적합.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 0.5–2 µg/Test
Neutralization (Neu)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | R004 |
| Immunogen | Recombinant Human IL-17R/IL-17RA/CD217 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | arginine/histidine with 0.02% Tween 80, 120mM NaCl |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866610 |
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It induces maturation of CD34-positive hematopoietic precursors into neutrophils.
IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F.
IL-17A and its receptor are implicated in inflammatory and autoimmune diseases such as rheumatoid arthritis.
Defects in IL-17RA cause familial candidiasis type 5 (CANDF5), a rare disorder with altered immune responses and impaired clearance of fungal infections.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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