Thermo Fisher Scientific Phospho-MAPKAPK2 (Ser272) Polyclonal Antibody
MAPKAPK2의 Ser272 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot, IHC(P), Dot blot에 사용 가능. Human에 반응하며, Mouse에서 교차 반응 예측. Protein A 및 항원 친화 크로마토그래피로 정제. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Dot Blot (DB) | 1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977076 |
Product Specific Information
This antibody is predicted to react with mouse and rabbit based on sequence homology.
Target Information
MAPKAPK2 mediates p38 and ERK signaling in vivo. It is involved in various cellular processes such as stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation.
MAPKAPK2 encodes a member of the Ser/Thr protein kinase family and is regulated through direct phosphorylation by p38 MAP kinase.
Heat shock protein HSP27 is one of the known substrates of this kinase in vivo. Two transcript variants encoding different isoforms have been identified for MAPKAPK2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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