Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI4H8), TrueMAB
Human PDE2A 단백질에 특이적인 Mouse IgG1 단클론 항체로 Western blot과 Flow cytometry에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Full length human recombinant protein of human PDE2A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kDa cyclic nucleotide phosphodiesterase with three isoforms (PDE2A1, PDE2A2, PDE2A3) generated by alternative splicing.
It hydrolyzes both cAMP and cGMP, with higher efficiency for cGMP. PDE2A is highly expressed in the brain, particularly in the cerebellum and neocortex.
It has been associated with penile erectile dysfunction and regulation of fluid and inflammatory cell transport across the endothelial barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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