Thermo Fisher Scientific SLC7A5 Polyclonal Antibody
SLC7A5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역세포염색에 적합합니다. 고순도 항원 친화 정제 방식으로 제조되었으며, 인간, 마우스, 랫트에 반응합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human LAT1/SLC7A5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719868 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Solute carrier family 7 member 5 (SLC7A5), also known as large neutral amino acids transporter small subunit 1 (LAT1), is a protein encoded by the SLC7A5 gene in humans.
It mediates sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine, and tryptophan, in association with SLC3A2/4F2hc.
SLC7A5 is involved in cellular amino acid uptake, transport of L-DOPA across the blood-brain barrier, and transport of thyroid hormones (T3 and T4) across cell membranes in tissues such as placenta.
It acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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