Thermo Fisher Scientific 14-3-3 beta Polyclonal Antibody
Human 14-3-3 beta 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ELISA, IP에 적합합니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 보존제가 포함되지 않은 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human 14-3-3 beta/YWHAB protein (Met1–Asn246) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788370 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human 14-3-3 beta/YWHAB.
Target Information
14-3-3 proteins are a family of acidic, soluble proteins highly conserved across species from yeast to mammals. Seven isoforms (beta, gamma, epsilon, eta, zeta, sigma, and tau/theta) are encoded by distinct genes in mammals and form homo- and hetero-dimeric cup-shaped structures.
These proteins interact with over 100 binding partners and regulate key proteins involved in signal transduction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology.
Most 14-3-3 interactions require phosphorylation of serine or threonine residues in target sequences. This protein is abundantly expressed in the brain and has been detected in cerebrospinal fluid of patients with various neurological disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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