Thermo Fisher Scientific Mre11 Polyclonal Antibody
MRE11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, FFPE 조직에서는 citrate buffer(pH 6.0) 전처리 권장. DNA 이중가닥 절단 복구 연구에 활용 가능.
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Thermo Fisher Scientific Mre11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:400–1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between 1 and 50 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex.
This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity, and meiosis.
The complex possesses single-stranded endonuclease activity and double-strand-specific 3′–5′ exonuclease activity provided by MRE11.
RAD50 binds DNA ends and holds them in close proximity.
Mutations in the gene may result in ataxia-telangiectasia-like disorder 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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