Thermo Fisher Scientific Epstein Barr Virus Polyclonal Antibody
Epstein-Barr 바이러스 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. 인간 시료에 반응하며, 친화 크로마토그래피로 정제됨. 액상 형태로 -20°C에서 보관. 연구용으로 EBV 관련 단백질 검출에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| ELISA | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Epstein-Barr virus TK (Accession P03177), corresponding to amino acid residues A9–H29. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900107 |
Product Specific Information
Antibody detects endogenous levels of total KITH_EBV.
Target Information
Epstein-Barr virus (EBV) is a human herpes virus associated with conditions such as Hodgkin’s disease and Burkitt’s lymphoma, and is the causative agent of mononucleosis in adolescents. EBV latently infects B lymphocytes, which express EBV nuclear antigens and latent proteins LMP1, LMP2A, and LMP2B.
LMP2A forms aggregates in the plasma membrane of B lymphocytes, functioning as a negative regulator of Src and Syk protein tyrosine kinases. Studies indicate that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV-immortalized B cells in vitro and may play a role in maintaining latent EBV infection in peripheral blood B cells.
EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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