Thermo Fisher Scientific TCCR Polyclonal Antibody
Human IL27RA 유래 펩타이드 항원을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합하며 내인성 IL27RA 단백질 검출 가능. 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL27RA (Accession Q6UWB1), corresponding to amino acid residues T30–T80. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818788 |
Product Specific Information
Antibody detects endogenous levels of total IL27RA.
Target Information
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) and type 2 (Th2) cells, which are critical for cell-mediated and humoral immune responses, respectively.
Th1 differentiation is mainly influenced by IL12, while IL4 drives Th2 differentiation. Mice deficient in these cytokines, their receptors, or associated transcription factors exhibit impaired Th1 or Th2 responses.
The human IL27RA gene encodes a protein similar to the mouse T-cell cytokine receptor Tccr and is predicted to be a glycosylated transmembrane protein.
Diseases associated with IL27RA include Hyper IgE Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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