Thermo Fisher Scientific DCT Polyclonal Antibody
DCT 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합합니다. 인간과 생쥐 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA5101647
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DCT (Accession P40126), corresponding to amino acid residues Q56–C106 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851081 |
Product Specific Information
This antibody detects endogenous levels of total TRP2/DCT.
Target Information
The TYR-related proteins, TRP1 and TRP2, are specifically expressed in melanocytes and contribute to melanin synthesis within melanosomes. These proteins share a similar transmembrane region, contain two metal-binding regions and a cysteine-rich EGF motif, and are localized in the melanosomal membrane. Each protein has distinct catalytic activity and collectively contributes to melanin biosynthesis. TRPs are believed to form a multi-enzyme complex, with TRP1 stabilizing TYR in melanocytes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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