Thermo Fisher Scientific Lamin A/C Polyclonal Antibody
Lamin A/C 단백질 검출용 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 IHC(Paraffin) 분석에 적합하며, 인간 및 생쥐에 반응합니다. 고순도 항원 친화 크로마토그래피 정제 제품으로, 다양한 종에 높은 예측 반응성을 보입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Lamin A/C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792465 |
Product Specific Information
- Keep as concentrated solution.
- Predicted Reactivity: Mouse (98%), Rat (98%), Dog (98%), Pig (98%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (98%)
- Positive Control: A431, NIH-3T3, HeLa Nucleus
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. They exist in three forms (A, B, and C) and are expressed in various cell types. Lamins A and C are alternatively spliced products of the LMNA gene, which is associated with several disorders, including:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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