Thermo Fisher Scientific TCCR Monoclonal Antibody (263503)
TCCR 단클론 항체(클론 263503)는 Mouse 시료에 반응하며, Western blot과 Flow cytometry에 적합합니다. IL-27 R alpha/WSX-1/TCCR 항원을 면역원으로 사용하였으며, Lyophilized 형태로 제공됩니다. 단백질 A/G 정제, PBS + 5% trehalose 버퍼에 보존됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 263503 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse IL-27 R alpha/WSX-1/TCCR (Gly29–Lys510) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610122 |
Product Specific Information
- In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse gp130 or recombinant human IL-27 R alpha is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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