Thermo Fisher Scientific ELOVL7 Polyclonal Antibody
Thermo Fisher Scientific의 ELOVL7 Polyclonal Antibody는 인간 ELOVL7 단백질을 인식하는 토끼 IgG 기반 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 지방산 신장 관련 연구 및 암 대사 연구에 적합합니다.
- 카탈로그번호
- PA557615
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: [Reference Placeholder]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: [Reference Placeholder]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ELOVL7. Recombinant protein control fragment (Product #RP-96918). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641002 |
Product Specific Information
Immunogen sequence:
MAFSDLTSRT VHLYDNWIKD ADPRVEDWLL M
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 48%
Target Information
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1.
Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of the fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0–) and may be involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
The metabolic pathways of long-chain fatty acids play an important role in maintaining membrane lipid composition and generating signaling precursors such as eicosanoids and sphingosine-1 phosphate.
Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by microRNA miR-219.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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