Thermo Fisher Scientific CENPT Polyclonal Antibody
CENPT 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 사람과 생쥐 시료에 반응하며, 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며, -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CENPT (Accession Q96BT3), corresponding to amino acid residues P423–M473 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850228 |
Product Specific Information
Antibody detects endogenous levels of total CENPT.
Target Information
CENPT is a component of the CENPA-NAC (nucleosome-associated) complex, which plays a central role in kinetochore protein assembly, mitotic progression, and chromosome segregation.
The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
CENPT is part of the CENP-T-W-S-X complex that binds and supercoils DNA, essential for kinetochore assembly and function. It is one of the inner kinetochore proteins required for normal chromosome organization and mitotic progression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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