Thermo Fisher Scientific FLT3 (CD135) Polyclonal Antibody
Rabbit polyclonal antibody against FLT3 (CD135). Western blot, IHC, ELISA에 적합하며, 세포 증식 및 분화 관련 신호전달 연구에 활용. 동결건조 형태로 제공되며, 재구성 시 500 µg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL | - |
| ELISA | 1–5 µg/mL (capture) | - |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human FLT3 / CD135 recombinant protein (Position: E61–E294) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746385 |
Product Specific Information
Add 0.2 mL of distilled water to reconstitute. The resulting concentration will be 500 µg/mL.
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Upon ligand binding, the receptor forms homodimers and undergoes autophosphorylation, activating signaling pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations causing constitutive activation of this receptor are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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