Thermo Fisher Scientific STIM2 Polyclonal Antibody
STIM2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 등 다양한 종에 반응합니다. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific STIM2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Immunocytochemistry (ICC/IF): 1:25
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the sequence of human STIM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979276 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
In T lymphocytes, Ca++ entry following antigen-receptor binding occurs through store-operated Ca++-release-activated Ca++ (CRAC) channels composed of ORAI1 and STIM1. STIM1 acts as a Ca++ sensor and activates CRAC channels by migrating from ER-like Ca++ stores to the plasma membrane. A related molecule, STIM2, inhibits STIM1-mediated Ca++ entry and can form complexes with STIM1, suggesting a coordinated role in Ca++ regulation. At least three isoforms of STIM2 are known.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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