Thermo Fisher Scientific DLC1 Polyclonal Antibody
Human reactive rabbit polyclonal antibody for DLC1 detection. Suitable for ICC/IF applications with 0.25–2 µg/mL dilution. Affinity-purified, liquid form, unconjugated. Provides reliable tumor suppressor protein analysis in cancer research.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (Antigen range: 355–443). Recombinant protein control fragment (Product #RP-109847) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092092 |
Product Specific Information
Immunogen sequence:
MVLLIMKLDQ LDQDIENALS TSSSPSGTPT NLRRHVPDLE SGSESGADTI SVNQTRVNLS SDTESTDLPS STPVANSGTK PKTTAIQGIAntigen sequence identity:
Mouse 79%; Rat 28%
Target Information
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins, which regulate small GTP-binding proteins. GAP family proteins are involved in signaling pathways that control cytoskeletal changes.
DLC1 functions as a tumor suppressor gene in several cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants exist due to alternative promoters and splicing.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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