Thermo Fisher Scientific KMT2C Polyclonal Antibody
Thermo Fisher Scientific의 KMT2C Polyclonal Antibody는 인간 KMT2C 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, 안정적 PBS/glycerol buffer 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 505–596). Recombinant protein control fragment (Product #RP-109822). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091770 |
Product Specific Information
- Immunogen sequence:
DTQLKEEYIC MYCKHLGAEM DRLQPGEEVE IAELTTDYNN EMEVEGPEDQ MVFSEQAANK DVNGQESTPG IVPDAVQVHT EEQQKSHPSE SL - Antigen sequence identity: Mouse 67%; Rat 67%
Target Information
Histone methyltransferase. Methylates Lys-4 of histone H3, which is a specific epigenetic activation tag. Central component of the MLL2/3 complex, a coactivator of nuclear receptors involved in transcriptional coactivation. KMT2C/MLL3 may serve as the catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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