Thermo Fisher Scientific KMT2C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 505-596. Recombinant protein control fragment (Product #RP-109822). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KMT2C,uniProtId:Q8NEZ4-1,ncbiNodeId:9606,antigenRange:505-596,antigenLength:4911,antigenImageFileName:PA5-144903_KMT2C_Q8NEZ4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144903_KMT2C_Q8NEZ4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091770

Product Specific Information

Immunogen sequence: DTQLKEEYIC MYCKHLGAEM DRLQPGEEVE IAELTTDYNN EMEVEGPEDQ MVFSEQAANK DVNGQESTPG IVPDAVQVHT EEQQKSHPSE SL

Antigen sequence identity: Mouse 67%; Rat 67%

Target Information

Histone methyltransferase. Methylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.