Thermo Fisher Scientific alpha N-Catenin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CTNNA2(Accession P26232), corresponding to amino acid residues T21-F71. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha N-Catenin,uniProtId:P26232-1,ncbiNodeId:9606,antigenRange:21-71,antigenLength:953,antigenImageFileName:PA5-103713_alpha_N-Catenin_P26232-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103713_alpha_N-Catenin_P26232-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853046

Product Specific Information

Antibody detects endogenous levels of total CTNNA2.

Target Information

The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.