Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI1E8), TrueMAB
C17orf37 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 유세포분석에 사용 가능. 인간 단백질에 반응하며, 고순도 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되며, 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E8 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The ERBB2 (neu/HER2) oncogene plays a key role as a predictor of patient outcome and therapeutic response in breast cancer.
C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. It is located on chromosome 17q12, approximately 505 nucleotides from the 3' end of the ERBB2 oncogene, the target for trastuzumab (Herceptin) therapy.
The genes encoding C35 and ERBB2 are arranged tail-to-tail. The ORF37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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