Thermo Fisher Scientific BFSP2 Monoclonal Antibody (OTI1A11), TrueMAB
BFSP2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. 인간 시료 반응성, 비결합형 동결건조 형태. 재구성 후 1 mg/mL 농도 유지, 연구용으로 사용. 렌즈 섬유세포 분화 관련 단백질 탐지에 유용.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 184–415 of human BFSP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
More than 99% of the vertebrate ocular lens is composed of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, phakinin (BFSP2) and filensin, are expressed after fiber cell differentiation begins. Both proteins form a unique cytoskeletal element called the beaded filament (BF).
Mutations in BFSP2 are associated with juvenile-onset progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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