Thermo Fisher Scientific PIK3R4 Monoclonal Antibody (1D4)
PIK3R4 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, PBS 버퍼에 보존된 액상 형태입니다. 오토파지 및 엔도사이토시스 관련 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D4 |
| Immunogen | PIK3R4 (NP_055417, 1259–1358 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AGSDMKIRFW DLAYPERSYV VAGSTSSPSV SYYRKIIEGT EVVQEIQNKQ KVGPSDDTPR RGPESLPVGH HDIITDVATF QTTQGFIVTA SRDGIVKVWK
Target Information
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different complex forms are believed to play a role in multiple membrane trafficking pathways:
- PI3KC3-C1: involved in initiation of autophagosomes
- PI3KC3-C2: involved in maturation of autophagosomes and endocytosis
Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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