Thermo Fisher Scientific CD155 Monoclonal Antibody (2H7CD155), FITC, eBioscience
CD155 단백질을 인식하는 FITC 결합 단클론 항체로, Flow Cytometry에 최적화됨. 인간 시료 반응성, Mouse IgG1 카파 아이소타입. 488 nm/520 nm 형광 특성. 세포 부착 및 NK 세포 활성 관련 연구에 적합.
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Thermo Fisher Scientific CD155 Monoclonal Antibody (2H7CD155), FITC, eBioscience
Applications
- Flow Cytometry (Flow)
Tested dilution: 5 µL (0.25 µg)/test
View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H7CD155 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2815033 |
Available Formats
Product Specific Information
The monoclonal antibody 2H7CD155 recognizes CD155, also known as the poliovirus receptor. CD155 is a member of the immunoglobulin superfamily with four isoforms; only the alpha and delta forms are expressed on the membrane of monocytes, prostate cancer cells, and neurectodermal or monocytic tumor cell lines. CD155 is also present during mid-gastrulation in embryonic development.
CD155 plays roles in:
- Cell adhesion via interaction with vitronectin (ECM component)
- NK cell-mediated tumor killing
Ligands for CD155 include CD226 and CD96. Blocking CD155 is under investigation for therapeutic prevention of poliovirus variants.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-diluted and validated on U937 cells
Use at 5 µL (0.25 µg) per test (100 µL final volume; 10⁵–10⁸ cells/test recommended).
Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
Target Information
The gene encoding CD155 produces a transmembrane glycoprotein of the immunoglobulin superfamily.
- External domain: Mediates attachment to vitronectin
- Intracellular domain: Interacts with dynein light chain Tctex-1/DYNLT1
- Function: Serves as the cellular receptor for poliovirus replication
- Found only in primate lineage
- Multiple transcript variants exist
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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