Thermo Fisher Scientific KChIP2 Monoclonal Antibody (OTI2D2)
KChIP2 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 적합합니다. Human 시료에 반응하며, 고순도 Affinity Chromatography로 정제되었습니다. 안정한 액상 형태로 -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full length human recombinant protein of KCNIP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724550 |
Target Information
Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential, while in the brain these channels prevent reverse-propagation of action potentials.
KChIPs (Kv channel interacting proteins) are calcium-binding proteins associated with Kv4 channels that modulate their function.
- KChIP1: Expressed in the brain
- KChIP2: Expressed in the brain, heart, and lung; has three isoforms (a, b, and c)
- KChIP3 (Calsenilin/DREAM): Expressed in the brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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