Thermo Fisher Scientific Lambda light chain Monoclonal Antibody (A8G5)
인간 Lambda light chain을 인식하는 mouse monoclonal antibody입니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합합니다. 단백질 A로 정제된 고순도 항체이며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific Lambda light chain Monoclonal Antibody (A8G5)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A8G5 |
| Immunogen | Constant region of natural protein (constant region of light chain lambda chain) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931391 |
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa).
Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is approximately 70:30.
Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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