Thermo Fisher Scientific PER3 Recombinant Rabbit Monoclonal Antibody (ARC1893)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1893

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 10-100 of human PER3 (P56645) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PER3,uniProtId:P56645-1,ncbiNodeId:9606,antigenRange:10-100,antigenLength:1201,antigenImageFileName:MA5-38036_PER3_P56645-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38036_PER3_P56645-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897954

Product Specific Information

Positive Samples: HeLa, Mouse lung, Mouse kidney, Rat lung

Immunogen sequence: GRRGAKDEAL GEESGERWSP EFHLQRKLAD SSHSEQQDRN RVSEELIMVV QEMKKYFPSE RRNKPSTLDA LNYALRCVHS VQANSEFFQI L

Target Information

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.